Signal Transduction

The Department of Biological Chemistry is composed of faculty members that form an intellectually exciting community. The diverse research interests focus on understanding the chemistry and biochemistry of life processes. Faculty members are very active and interactive and work in a culture that encourages the free exchange of ideas while fostering exciting collaborations within and outside the department. Such interactions strongly enhance the ability of each member to make seminal discoveries that cross scientific disciplines.

All Areas

Gene Regulation

Metabolism & Energetics

Protein Fold ing & Enzymology

Microbiology & Immunology

Neurobiology

Cellular Organization & Trafficking

Human Disease

Michael Caterina, M.D., Ph.D.
caterina@jhmi.edu
410-502-5457

TRP channel function in thermosensation, pain, and inflammation

Robert N. Cole, Ph.D.
rcole@jhmi.edu
410-614-6968

Mass spectrometry strategies to characterize proteins and their modifications in malnutrition, neurological diseases and cancer

Seth Margolis, Ph.D.
smargol7@jhmi.edu
410-502-5362

Molecular Mechanisms of Synapse Formation in Development and Disease

Mollie K. Meffert, M.D., Ph.D.
mkm@jhmi.edu
410-502-2570

The Regulation of Neuronal Gene Expression in Health and Disease

Joel L. Pomerantz, Ph.D.
joel.pomerantz@jhmi.edu
443-287-3100

Functional Specificity and Design of Signal Transduction Pathways

Daniel Raben, Ph.D.
draben@jhmi.edu
410-955-1289

Structure, function, regulation and interfacial enzymology of lipid metabolizing enzymes involved in signal transduction cascades; biochemistry and chemistry of lipids involved in signaling cascades.

Michael Wolfgang, Ph.D.
mwolfga1@jhmi.edu
443-287-7680

Cellular and organismal metabolism

Natasha Zachara, Ph.D.
nzachara@jhmi.edu
410-955-7049

O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Surival.