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Karen Reddy
Assistant Professor of Biological Chemistry
Johns Hopkins University School of Medicine

855 N. Wolfe St
Rangos 574
Baltimore, MD 21205
office tel: (443)287-7216
lab tel:
Fax:
Email: kreddy4@jhmi.edu
CV
Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation

Reddy, K.L. and Singh, H.S. (2008) “Using molecular tethering to analyze the role of nuclear compartmentalization in the regulation of mammalian gene activity”, Methods “Visualization of molecular processes in cells using fluorescence imaging”,

Reddy, K.L*., Johnson, K.J.*, and Singh, H.S. (2008) Signaling and transcriptional control coordinating V(D)J recombination and B cell development” "V(D)J Recombination", edited by Dr. Ferrier, Landes Bioscience

Reddy, K.L.*, Schlimgen, R.*, Singh, H.S. and Krangel, M. (2008) “The Role of Nuclear Localization in Regulating Tcrb Recombination and Allelic Exclusion” Submitted and out for review Nature Immunology (*co-first authors)

Reddy, K.L., Zullo, J.M. Bertolino, E. and Singh, H.S. (2008) “Mammalian gene repression mediated by inducible repositioning to the nuclear membrane”, Nature, 452(7184):243-7

Reynaud, D, DeMarco, I. , Reddy, K.L., Schjerven, H, Bertolino, E., Smale, S.T., Winandy, S. and Singh, H.S. (2008) “Key features of pro-B cells are specifically regulated by Ikaros”, Nature Immunology

Bertolino, E., Reddy, K.L., Medina, K. L., Parganas, E., Ihle, J., and Singh, H. (2005). “Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5” Nature Immunology 6, 836-843.

Medina, K. L., Pongubala, J. M. R., Reddy, K. L., Lancki, D. W., DeKoter, R., Kieslinger, M., Grosschedl, R., and Singh, H. (2004). “Assembling a Gene Regulatory Network for Specification of the B Cell Fate” Developmental Cell 7, 607-617.

 
Recent Publications

Reddy, K.L. and Singh, H.S. (2008) “Using molecular tethering to analyze the role of nuclear compartmentalization in the regulation of mammalian gene activity”, Methods “Visualization of molecular processes in cells using fluorescence imaging”,

Reddy, K.L*., Johnson, K.J.*, and Singh, H.S. (2008) Signaling and transcriptional control coordinating V(D)J recombination and B cell development” "V(D)J Recombination", edited by Dr. Ferrier, Landes Bioscience

Reddy, K.L.*, Schlimgen, R.*, Singh, H.S. and Krangel, M. (2008) “The Role of Nuclear Localization in Regulating Tcrb Recombination and Allelic Exclusion” Submitted and out for review Nature Immunology (*co-first authors)

Reddy, K.L., Zullo, J.M. Bertolino, E. and Singh, H.S. (2008) “Mammalian gene repression mediated by inducible repositioning to the nuclear membrane”, Nature, 452(7184):243-7

Reynaud, D, DeMarco, I. , Reddy, K.L., Schjerven, H, Bertolino, E., Smale, S.T., Winandy, S. and Singh, H.S. (2008) “Key features of pro-B cells are specifically regulated by Ikaros”, Nature Immunology

Bertolino, E., Reddy, K.L., Medina, K. L., Parganas, E., Ihle, J., and Singh, H. (2005). “Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5” Nature Immunology 6, 836-843.

Medina, K. L., Pongubala, J. M. R., Reddy, K. L., Lancki, D. W., DeKoter, R., Kieslinger, M., Grosschedl, R., and Singh, H. (2004). “Assembling a Gene Regulatory Network for Specification of the B Cell Fate” Developmental Cell 7, 607-617.

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