Below is a list of BCMB faculty listed alphabetically. You may also return to the list of BCMB faculty listed by departmental affiliation.

A

Ambinder, Richard F.
Virology and human cancer; antiviral therapy; antitumor therapy; lymphoma pathogenesis and treatment

Amzel, L. Mario
Structural enzymology of redox and phosphoryl-transfer enzymes: MICAL, VP14, PI3K, and Nudix hydrolases. Selected areas of structural thermodynamics.

Andrew, Deborah
Organogenesis in a model system: Formation of the Drosophila salivary gland and trachea

B

Baraban, Jay
Molecular mechanisms of neuronal plasticity

Bergles, Dwight
Synaptic signaling and neuron-glia interactions in the CNS

Blackshaw, Seth
Molecular basis of cell specification in vertebrate retina and hypothalmus

Boeke, Jef
Transposition mechanisms; yeast genetics; transcriptional silencing

C

Caterina, Michael
Molecular mechanisms of thermosensation and nociception

Chen, Elizabeth
Molecular and cellular mechanisms of myoblast fusion

Claypool, Steven
The interplay of lipids and proteins in mitochondrial physiology and pathophysiology.

Clements, Janice
Molecular Pathogenesis of SIV & HIV

Cole, Philip
Chemical approaches to the study of signal transduction, gene expression, and circadian rhythm.

Corden, Jeffry
RNA Polymerase II Phosphorylation and Transcription Regulation

Cormack, Brendan
Fungal pathogenesis: the host-pathogen interaction for the yeast pathogen Candida glabrata

Cotter, Robert
Development of time-of-flight and ion trap mass spectrometry; applications of MALDI and electrospray mass spectrometry to immunology, protein structure analysis and genomics

Coulombe, Pierre A.
Structural and signaling roles of keratin cytoskeletal assemblies; Epithelial differentiation and homeostasis in health and disease

Craig, Nancy L.
Genome plasticity, protein-DNA machines

Craig, Susan
Cytoskeletal proteins in Cell Adhesion and Motility

D

Desiderio, Stephen
Mechanisms of Development in the Immune System

Devreotes, Peter
Genetic analysis of chemotaxis in eukaryotic cells

Dong, Xinzhong
Molecular and Genetic Studies of Pain-sensing Neurons

E

Englund, Paul
Biochemistry and molecular biology of parasitic protozoa

Espenshade, Peter
Mechanisms of Molecular Sensing

Ewald, Andrew
Cellular mechanisms and molecular regulation of epithelial morphogenesis during development and breast cancer

F

Feinberg, Andrew
Epigenetics in development and disease; genomic imprinting

G

Gibson, D. Wade
Herpes virus proteins: synthesis, structure, and function during replication.

Ginty, David
Developmental Neuroscience

Gould, Stephen
Exosome biogenesis, retrovirus budding, alloimmunity, and animal evolution.

Green, Rachel
Molecular switches in the ribosome and their role in regulation

Greider, Carol
Telomeres and telomerase in stem cell failure and cancer

Guggino, William
Structure/function studies of Cl- and water channels.

H

Hardwick, J. Marie
Molecular mechanisms of programmed cell death and its role in viral pathogenesis

Hart, Gerald
Roles of cytoplasmic and nuclear glycosylation in transcription, oncogene function, neurodegenerative disease, and in diabetes

Hayward, Gary
Herpesvirus regulation of cellular factors

Hayward, S. Diane
Herpesvirus Interactions with Cell Signaling Pathways

Hoh, Jan
Cellular and molecular biophysics; atomic force microscopy; engineered cellular microenvironments; protein micropatterning

Hubbard, Ann
Trafficking of Copper-ATPases and Molecular Determinants of Polarity in Epithelial Cells.

Huganir, Richard
Regulation of Neurotransmitter Receptor Function and Synaptic Plasticity in the Brain

I

Iijima, Miho
Lipid Signaling in Chemotaxis

Inoue, Takanari
Our lab will use inducible perturbation and simultaneous real-time fluorescent imaging to reveal how elementary signaling modules can be integrated to generate complex chemotactic behaviors. We will also develop and implement an innovative method for probing fast, local signaling events in polarized cells.

J

Jensen, Robert
Mitochondrial dynamics, protein targeting, yeast molecular genetics.

K

Kolodkin, Alex
Molecular Mechanisms of Neuronal Growth Cone Guidance

Kupfer, Abraham (Avi)
Signaling, cell-cell interaction, intercellular communication, immune cell activation, multi-dimensional imaging, novel biosensors.

L

Leahy, Daniel
Three-dimensional structure of proteins and protein complexes involved in cell-cell and cell-matrix interaction and signaling

Lee, Se-Jin
Growth and differentiation factors, mammalian development

Li, Min
Molecular regulation of potassium channels in health and in disease

Liu, Jun
Chemical biology and molecular biology; use of small molecules as probes to elucidate mechanisms of signal transduction, angiogenesis and cell proliferation

Lorsch, Jon
Mechanisms of eukaryotic translation initiation

Lutsenko, Svetlana
Copper homeostasis: mechanism of transport, protein and metabolic networks, integrative approches to human disease

M

Machamer, Carolyn
Intracellular protein trafficking; Golgi complex structure/function; apoptosis; intracellular virus assembly; coronaviruses

Maloney, Peter
Mechanisms of membrane transport; reconstitution and crystallization of membrane function; cystic fibrosis

Marsh-Armstrong, Nick
Gene regulation, development and disease of the vertebrate retina

Matunis, Erika
Signals Regulating Stem Cell Self-renewal

Meffert, Mollie K.
The Regulation of Neuronal Gene Expression in Health and Disease

Meyers, Caren L. Freel
Organic and medicinal chemistry, chemical biology: drug delivery mechanisms in bacteria; development of antibiotic prodrug strategies; study of bacterial isoprenoid biosynthesis; combinatorial biosynthesis; development of potential therapeutic agents

Michaelis, Susan
Yeast and mammalian cell biology; progeria and lamin A processing; ER quality control and cystic fibrosis, ABC transporters

Montell, Craig
TRP channels: From Sensory Signaling to Animal Behavior and Neurodegeneration

Montell, Denise
Cellular and Molecular Dynamics of Cell Migration

N

Nathans, Jeremy
Molecular mechanisms of retinal development and disease; the role of Frizzled receptors in mammalian development.

P

Pan, Duojia D.J.
Molecular genetics of tumor suppression genes and oncogenes

Pandey, Akhilesh
Signal transduction; Mass spectrometry; Bioinformatics; Cancer biomarkers

Pedersen, Peter
Cell energetics, its molecular and chemical basis and relationship to both disease and to the discovery of new therapies.

Pevsner, Jonathan
Molecular basis of neurological disorders

Pitha-Rowe, Paula

Pomerantz, Joel L.
Functional Specificity and Design of Signal Transduction Pathways

R

Raben, Daniel
Biochemistry and chemistry of lipids and lipid metabolizing enzymes involved in signaling cascades

Rao, Rajini
Discovery and molecular mechanisms of novel ion transporters.

Reddy, Karen
Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation

Reed, Randall
Molecular mechanisms of signal transduction and neurogenesis in the olfactory system

Reeves, Roger
Mechanisms of gene action in aneuploidy; complex genetic traits.

Robinson, Douglas
Cytokinesis and Cell Shape Control

Ronnett, Gabriele
Developmental Neuroscience

S

Schnaar, Ronald
Molecular basis of cell-cell interactions in the nervous system; glycobiology

Sesaki, Hiromi
Molecular Mechanisms and Physiological Roles of Mitochondrial Fusion and Division

Seydoux, Geraldine
Embryonic Polarity and the Soma-Germline Dichotomy

Shapiro, Theresa
Molecular pharmacology of antiparasitic drugs

Siliciano, Robert
Host-virus interaction in HIV infection

Snyder, Solomon H.
Neural Signaling

Sockanathan, Shanthini
Cell fate specification in the central nervous system

Sollner-Webb, Barbara
(1) Nuclear DNA organization and (2) RNA Editing

Soloski, Mark
Structure and function of the genes and gene products of the mammalian major histocompatibility complex

Spencer, Forrest

Stäger, Simona
Immunoparasitology; CD8+ T-cells; Leishmania; vaccination

Stivers, James
Structural and Chemical Biology of Uracil Metabolism and Applications to Cancer Therapy, Viral Pathogenesis and Acquired Immunity

T

Taverna, Sean
Histone and chromatin modifications, epigenetics and gene function, identification of histone binding modules, and small RNA directed gene silencing.

U

Urban, Sinisa
Biochemistry, cell and chemical biology of intra-membrane proteases in cell signalling during development and host-cell invasion by pathogens

W

Wade, Herschel
Molecular basis of multi-ligand•receptor specificity, ligand-dependent transcriptional regulation and bacterial multidrug resistance.

Watkins, Paul
Fatty Acid Activation Enzymes

Wilson, Katherine
Nuclear envelope proteins and human disease

Wolberger, Cynthia
Structural and mechanistic basis of transcriptional regulation

Wolfgang, Michael
CNS control of metabolism; Neurochemistry: novel metabolic enzymes of the CNS.

Wong, Guang William
“Novel Fat tissue-derived endocrine mediators; insulin resistance, diabetes, and obesity”

Worley, Paul
Molecular mechanism of neuronal plasticity

X

Xiao, Jie
Quantitative understanding of gene expression and cell division at the single molecule and single cell levels. Single molecule fluorescence microscopy, live cell imaging, fluorescent reporter development.

Y

Yang, Joy
Regulation of cell migration by cell-ECM adhesion and integrin signaling.

Yau, King-Wai
Cellular and Molecular Neuroscience

Z

Zachara, Natasha
O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Surival.

Zack, Donald
Molecular approaches to the study of retinal development and function

Zhang, Jin
Spatiotemporal Regulation of Protein Kinases and Second Messengers.

Zhu, Heng
Signal Transduction, protein network, host-pathogen interaction, protein chip approach to study proteomics