Karen Reddy
| Department Affiliation |
Primary: Biological Chemistry
Secondary: (none)
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| Rank |
Faculty |
| Phone Numbers |
Office: (443)287-7216
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| Email |
kreddy4@jhmi.edu |
| School of Medicine Address |
855 N. Wolfe St
Rangos 574
Baltimore, MD 21205
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Research Topic:
Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation
Reddy, K.L. and Singh, H.S. (2008) “Using molecular tethering to analyze the role of nuclear compartmentalization in the regulation of mammalian gene activity”, Methods “Visualization of molecular processes in cells using fluorescence imaging”,
Reddy, K.L*., Johnson, K.J.*, and Singh, H.S. (2008) Signaling and transcriptional control coordinating V(D)J recombination and B cell development” "V(D)J Recombination", edited by Dr. Ferrier, Landes Bioscience
Reddy, K.L.*, Schlimgen, R.*, Singh, H.S. and Krangel, M. (2008) “The Role of Nuclear Localization in Regulating Tcrb Recombination and Allelic Exclusion” Submitted and out for review Nature Immunology (*co-first authors)
Reddy, K.L., Zullo, J.M. Bertolino, E. and Singh, H.S. (2008) “Mammalian gene repression mediated by inducible repositioning to the nuclear membrane”, Nature, 452(7184):243-7
Reynaud, D, DeMarco, I. , Reddy, K.L., Schjerven, H, Bertolino, E., Smale, S.T., Winandy, S. and Singh, H.S. (2008) “Key features of pro-B cells are specifically regulated by Ikaros”, Nature Immunology
Bertolino, E., Reddy, K.L., Medina, K. L., Parganas, E., Ihle, J., and Singh, H. (2005). “Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5” Nature Immunology 6, 836-843.
Medina, K. L., Pongubala, J. M. R., Reddy, K. L., Lancki, D. W., DeKoter, R., Kieslinger, M., Grosschedl, R., and Singh, H. (2004). “Assembling a Gene Regulatory Network for Specification of the B Cell Fate” Developmental Cell 7, 607-617.
Publications:
Reddy, K.L. and Singh, H.S. (2008) “Using molecular tethering to analyze the role of nuclear compartmentalization in the regulation of mammalian gene activity”, Methods “Visualization of molecular processes in cells using fluorescence imaging”,
Reddy, K.L*., Johnson, K.J.*, and Singh, H.S. (2008) Signaling and transcriptional control coordinating V(D)J recombination and B cell development” "V(D)J Recombination", edited by Dr. Ferrier, Landes Bioscience
Reddy, K.L.*, Schlimgen, R.*, Singh, H.S. and Krangel, M. (2008) “The Role of Nuclear Localization in Regulating Tcrb Recombination and Allelic Exclusion” Submitted and out for review Nature Immunology (*co-first authors)
Reddy, K.L., Zullo, J.M. Bertolino, E. and Singh, H.S. (2008) “Mammalian gene repression mediated by inducible repositioning to the nuclear membrane”, Nature, 452(7184):243-7
Reynaud, D, DeMarco, I. , Reddy, K.L., Schjerven, H, Bertolino, E., Smale, S.T., Winandy, S. and Singh, H.S. (2008) “Key features of pro-B cells are specifically regulated by Ikaros”, Nature Immunology
Bertolino, E., Reddy, K.L., Medina, K. L., Parganas, E., Ihle, J., and Singh, H. (2005). “Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5” Nature Immunology 6, 836-843.
Medina, K. L., Pongubala, J. M. R., Reddy, K. L., Lancki, D. W., DeKoter, R., Kieslinger, M., Grosschedl, R., and Singh, H. (2004). “Assembling a Gene Regulatory Network for Specification of the B Cell Fate” Developmental Cell 7, 607-617.
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