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Biological Chemistry
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Mass spectrometry

Mass Spectrometry and Proteomics FacilityOur facility has several mass spectrometers (two Thermo Orbitrap Velos, a Thermo Q-Exactive electrospray and an AB Sciex  Voyager DE-STR MALDI-TOF), as well as two-dimensional gel electrophoresis and gel imaging equipment including spot handling robotics (GE Healthcare). The electrospray MS instruments are interfaced with two dimensional nanoflow liquid chromatographic systems (Eksigent Technologies or Waters Corp.) for on-line separation, fragmentation, sequencing and identification of peptides. Consequently, we are well equipped and have extensive experience in protein microchemistry and microsequencing to aid you in separating, identifying and characterizing your proteins of interest.

Please call (410-614-6968) or email (rcole@jhmi.edu) the director your questions on the application of mass spectrometry to your research objectives.

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