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Department of
Biological Chemistry
Johns Hopkins University Medicine logo

The Department of Biological Chemistry is composed of faculty members that form an intellectually exciting community. The diverse research interests focus on understanding the chemistry and biochemistry of life processes. Faculty members are very active and interactive and work in a culture that encourages the free exchange of ideas while fostering exciting collaborations within and outside the department. Such interactions strongly enhance the ability of each member to make seminal discoveries that cross scientific disciplines.

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Michael Caterina photo
TRP channel function in thermosensation, pain, and inflammation

Robert N. Cole photo
Mass spectrometry strategies to characterize proteins and their modifications in malnutrition, neurological diseases and cancer

Ryuya Fukunaga photo
Mechanism and biology of small silencing RNAs

Erin Goley photo
Bacterial cell biology: cytoskeletal function during growth and division

Stephen Gould photo
Exosome biogenesis and retrovirus budding

Gerald Hart photo
Roles of cytoplasmic and nuclear glycosylation in transcription, oncogene function, neurodegenerative disease, and in diabetes

Seth Margolis photo
Molecular Mechanisms of Synapse Formation in Development and Disease

Mollie K. Meffert photo
The Regulation of Neuronal Gene Expression in Health and Disease

Tamara O'Connor photo
Molecular dissection of host-pathogen interactions and the evolution of virulence strategies in natural reservoirs

Akhilesh Pandey photo
Signal transduction; Mass spectrometry; Bioinformatics; Cancer biomarkers

Peter Pedersen photo
Cell energetics, its molecular and chemical basis and relationship to both disease and to the discovery of new therapies.

Joel L. Pomerantz photo
Functional Specificity and Design of Signal Transduction Pathways

Daniel Raben photo
Structure, function, regulation and interfacial enzymology of lipid metabolizing enzymes involved in signal transduction cascades; biochemistry and chemistry of lipids and lipid metabolizing enzymes involved in signaling cascades.

Karen Reddy photo
Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation

George Sack photo
Human amyloid A protein structure and pathophysiology

David Shortle photo
Protein folding; NMR characterization of partially folded proteins; protein structure prediction

Michael Wolfgang photo
Cellular and organismal metabolism

Natasha Zachara photo
O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Surival.

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